Dicero Poison and Great Sword Build Guide (April 2026)

There’s a point in Dicero where simple builds stop being enough. Enemies get tankier, fights last longer, and suddenly raw damage alone doesn’t always carry you. That’s where builds like Poison and Great Sword come in, offering two completely different answers to the same problem.

One slowly takes control of the fight over time. The other tries to end it before it even begins.

Poison Build Guide

Poison is not about burst. It’s about inevitability.

From the moment a fight starts, Poison begins stacking damage across enemies. Each stack may look small on its own, but the real strength comes from how those stacks persist, spread, and scale throughout the fight.

  • Applies poison stacks at the start of turns
  • Additional stacks are applied through rerolls
  • Each stack deals consistent damage over time
  • Stacks remain even after burst triggers

This means enemies are constantly losing health, even when you’re not directly attacking them.

What makes Poison powerful is that it doesn’t rely on perfect turns. Even average turns still contribute to your overall damage output.

  • Great for longer fights
  • Works well against multiple enemies
  • Doesn’t require precise execution
  • Damage continues passively

If you’re in a run where enemies feel too tanky, Poison gives you a way to outlast them.

Great Sword Build Guide

If Poison is about patience, Great Sword is about ending fights immediately.

This build transforms your basic attacks into heavy-hitting strikes and stacks massive damage bonuses through rerolls and combos. It’s straightforward, aggressive, and extremely satisfying when it works.

  • Converts basic attacks into Great Sword attacks
  • Gains damage bonuses from rerolls and combos
  • Focuses on high burst per turn

You’re not building over time. You’re maximizing every single hit.

Great Sword thrives in situations where fights can be decided quickly.

  • High burst damage
  • Strong early and mid game
  • Simple and reliable execution
  • Great for fast clears

If you enjoy seeing enemies disappear in one or two turns, this build delivers.

What makes Dicero interesting is how different builds can completely change the pacing of a run.

Poison slows the game down and gives you control. Great Sword speeds it up and forces outcomes quickly. Neither is strictly better, but each shines in the right situation.

The key is recognizing what your run needs and committing to that direction early. Mixing both usually weakens your overall strategy.